Formulation and Evaluation of Vilazodone Microspheres

Authors

  • Sameera Fatima Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana-500001,
  • Muna Unnisa Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana-500001,
  • Syeda Juveriya Mahmood Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana-500001,
  • Mohammed Qayam Uddin Khaleel Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana-500001,
  • Syeda Shafiya Firdous Jaffri Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana-500001,

Keywords:

Higuchi, Ethyl cellulose, Eudragit RL 100 and HPMC K4M Solvent evaporation method and microspheres.

Abstract

The aim of the study was to prepare Vilazodone microspheres using Solvent evaporation method using different polymer ratio. FT-IR studies revealed that there was no chemical interaction between the drug and polymer. The average particle size of the optimized formulation was found to be 166 μm. The in-vitro release behavior from all the Vilazodone microspheres was found to be Higuchi drug release kinetics and produced a sustained release over a period of 12 hours with better entrapment efficiency.

Dimensions

Published

2026-06-02

Issue

Vol. 14 No. 2 (2026): 2026 Volume -14 - Issue 2

Section

Articles
Copyright & Licensing

Copyright (c) 2026 International Journal of Pharmaceuticals and Health Care Research

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