Formulation And Evaluation Of Herbal Mosquito Repellent Cream

Abstract

The increasing interest in the harmful effects of synthetic chemical repellents has created a growing need for natural substitutes for mosquito repellents. The present study was undertaken to develop and test a herbal mosquito repellent cream from natural products like neem (Azadirachta indica), tulsi (Ocimum sanctum), and lemongrass (Cymbopogon citratus), which are well known for their insecticidal and mosquito-repellent activities. The main aims were to determine the physical characteristics, stability, safety for skin use, and mosquito-repelling activity of the cream. The cream formulation was done by isolating active constituents from neem, tulsi, and lemongrass and mixing them with a base cream. The physical characteristics of the creams, such as color, texture, and spreadability, were assessed, and all the formulations had a uniform, homogenous smooth texture without any evident separation or imperfections. The pH of the cream was within the optimal range of 5.0 to 6.0 and was suitable for use with the skin. Skin irritation testing was performed in human volunteers with no evidence of irritation, redness, or discomfort and showed that the cream is safe for topical application. The mosquito repellency test, conducted with Aedes aegypti mosquitoes, showed that the cream gave high levels of mosquito repellency, with the best formulation giving as much as 90% protection. This can be compared to synthetic chemical repellents such as DEET, proving the effectiveness of the herbal ingredients in repelling mosquitoes. Generally, the herbal mosquito repellent cream was found to be effective, stable, and safe to use. The findings indicate that it could be a promising natural alternative to chemical mosquito repellents, providing protection against mosquito-borne diseases in an environmentally friendly way. Further studies such as long-term field trials and incorporating more plant-based components may enhance its effectiveness and increase market potential. This formulation presents a viable, sustainable solution to the growing demand for natural repellents for mosquitoes in the global market.