A Study On Human Metapneumovius
Keywords:
vaccine development, antiviral therapy, supportive treatment, epidemiologyAbstract
Human metapneumovirus (HMPV) is a relative newly described virus. It was first isolated in 2001 and currently human viral infections. Retrospective serologic studies demonstrated the presence of HMPV antibodies in humans more than 50 years earlier. Although the virus was primarily known as causative agent of respiratory tract infections in children.HMPV is an important cause of respiratory infections in adults as well. Almost all children are infected by Hmpv below the age of five. The repeated infections through out life indicate transient immunity. HMPV infections usually are mild and self – limiting, but in the trail elderly and the immunocompromised patients, the virus is relatively difficult, diagnosis is mostly based on a nucleic acid amplification test, such as reverse transcriptase polymerase chain reaction. To date, no vaccine is available and treatment is supportive. However, ongoing research shows encouraging results. The aim of this paper is to review the current literature concerning HMPV Infections in adults, and discuss recent development in treatment and vaccination.
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