Crispr/Cas9 Enzyme Using For Editing Of Cancer Gene

Abstract

Clustered Regularly Interspaced Short Palindromic Repeats are DNA sequences that go by the acronym CRISPR. Scientists may now alter an organism's DNA thanks to a set of technologies known as genome editing, sometimes referred to as gene editing. Cancer. Mutations in various genes, including TP53, MLH1, BRCA1, and HLA-B, can result in cancer. Serious endometrial carcinoma is an extremely uncommon but aggressive kind of cancer that affects women, and it has been related to BRCA1 mutations. The use of CRISPR-Cas9 protein and other genome editing technologies to modify human genomes raises ethical questions. Somatic cells—those distinct from egg and sperm cells—are the only ones affected by the majority of the alterations brought about by genome editing. These alterations are exclusive to particular tissues and do not transfer from one generation to the next. The treatment and prevention of human diseases are highly interested in genome editing. These technologies make it possible to add, remove, or change genetic material at specific points along the genome sequence, including sickle cell disease, haemophilia, and cystic fibrosis, among other single-gene illnesses. Additionally, there is hope that it can help treat and prevent more complicated illnesses like cancer, heart disease, and mental illness.